Michael R Grever Selected Research

Pentostatin (Nipent)

1/2015	Reduced dose pentostatin for initial management of hairy cell leukemia patients who have active infection or risk of hemorrhage is safe and effective.
8/2013	Standard pentostatin dose reductions in renal insufficiency are not adequate: selected patients with steroid-refractory acute graft-versus-host disease.
3/2012	Hematologic improvement after flavopiridol treatment of pentostatin and rituximab refractory hairy cell leukemia.
6/2011	Hairy cell leukemia: a successful model for experimental therapeutics--pentostatin and new ideas.
2/2011	Modern strategies for hairy cell leukemia.
5/2010	Pentostatin and rituximab therapy for previously untreated patients with B-cell chronic lymphocytic leukemia.
10/2009	Long-term follow-up studies in hairy cell leukemia.
1/2009	Mcl-1 expression predicts progression-free survival in chronic lymphocytic leukemia patients treated with pentostatin, cyclophosphamide, and rituximab.
6/2007	Pentostatin, cyclophosphamide, and rituximab regimen in older patients with chronic lymphocytic leukemia.
1/2007	Combination chemoimmunotherapy with pentostatin, cyclophosphamide, and rituximab shows significant clinical activity with low accompanying toxicity in previously untreated B chronic lymphocytic leukemia.

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Michael R Grever Research Topics

Disease

56	B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia) 01/2022 - 06/2003
46	Neoplasms (Cancer) 01/2021 - 04/2002
17	Leukemia 02/2015 - 01/2003
16	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 12/2020 - 04/2002
14	Hairy Cell Leukemia 01/2021 - 03/2003
8	Lymphoma (Lymphomas) 01/2019 - 12/2005
7	Tumor Lysis Syndrome 06/2016 - 11/2007
5	Infections 01/2019 - 03/2007
5	Disease Progression 09/2015 - 03/2007
5	Non-Hodgkin Lymphoma (Lymphosarcoma) 01/2014 - 09/2004
4	Myelodysplastic Syndromes (Myelodysplastic Syndrome) 12/2020 - 04/2002
4	Multiple Myeloma 01/2019 - 11/2009
4	Hematologic Neoplasms (Hematological Malignancy) 02/2015 - 09/2003
4	Thrombocytopenia (Thrombopenia) 01/2013 - 04/2005
4	Neutropenia 01/2013 - 07/2010
4	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 09/2011 - 04/2007
3	Breast Neoplasms (Breast Cancer) 01/2020 - 11/2009
3	B-Cell Leukemia (Leukemia, B Cell) 09/2015 - 05/2009
3	Graft vs Host Disease (Graft-Versus-Host Disease) 08/2013 - 04/2005
3	Lymphadenopathy 03/2013 - 01/2009
3	Cytokine Release Syndrome 12/2009 - 01/2009
3	Residual Neoplasm 01/2009 - 10/2006
2	Exanthema (Rash) 10/2015 - 03/2011
2	Prolymphocytic Leukemia 08/2015 - 05/2015
2	Opportunistic Infections (Opportunistic Infection) 04/2015 - 12/2005
2	Melanoma (Melanoma, Malignant) 01/2015 - 01/2013
2	Rare Diseases (Rare Disease) 09/2014 - 02/2011
2	Vomiting 01/2013 - 01/2003
2	Nausea 01/2013 - 01/2003
2	Mantle-Cell Lymphoma (Lymphoma, Mantle Cell) 09/2012 - 01/2010
2	Lymphoproliferative Disorders (Lymphoproliferative Disorder) 01/2010 - 10/2004
1	Chromosome Aberrations (Chromosome Abnormalities) 12/2021
1	Fanconi Anemia (Fanconi's Anemia) 01/2020
1	Pancytopenia 01/2019

Drug/Important Bio-Agent (IBA)

24	alvocidib (flavopiridol)IBA 06/2016 - 06/2005
14	fludarabineIBA 05/2015 - 01/2003
14	Pentostatin (Nipent)FDA LinkGeneric 01/2015 - 03/2003
11	Rituximab (Mabthera)FDA Link 10/2013 - 03/2003
9	Cyclophosphamide (Cytoxan)FDA LinkGeneric 01/2015 - 12/2005
9	Proteins (Proteins, Gene)FDA Link 12/2014 - 07/2003
8	ibrutinibIBA 01/2022 - 04/2015
7	Pharmaceutical PreparationsIBA 01/2019 - 04/2005
7	Decitabine FDA Link 01/2018 - 09/2007
7	silvestrolIBA 02/2015 - 05/2009
7	Cyclin-Dependent Kinases (cdk Proteins)IBA 02/2015 - 01/2007
6	Lenalidomide (CC 5013)FDA Link 12/2020 - 10/2008
6	Purine NucleosidesIBA 09/2014 - 03/2003
5	Cytarabine (Cytosar-U)FDA LinkGeneric 12/2020 - 01/2003
5	Biological ProductsIBA 09/2015 - 09/2007
4	purineIBA 01/2021 - 10/2015
4	Paclitaxel (Taxol)FDA LinkGeneric 01/2020 - 06/2008
4	Bortezomib (Velcade)FDA Link 06/2014 - 05/2010
4	Ribonucleotide Reductases (Ribonucleotide Reductase)IBA 06/2014 - 06/2008
3	Agammaglobulinaemia Tyrosine KinaseIBA 01/2021 - 04/2015
3	Biomarkers (Surrogate Marker)IBA 01/2020 - 05/2015
3	GTI2040IBA 06/2014 - 06/2008
3	Cladribine FDA LinkGeneric 01/2014 - 10/2009
3	Adenosine DeaminaseIBA 08/2013 - 03/2003
3	Histone Deacetylases (Histone Deacetylase)IBA 02/2005 - 04/2002
3	DepsipeptidesIBA 02/2005 - 07/2003
2	VemurafenibIBA 01/2019 - 10/2015
2	Anti-Bacterial Agents (Antibiotics)IBA 01/2019 - 03/2015
2	Immunoglobulin Heavy Chains (Immunoglobulin Heavy Chain)IBA 07/2014 - 09/2008
2	SteroidsIBA 08/2013 - 04/2005
2	GlucuronidesIBA 03/2013 - 03/2009
2	triphosphoric acid (triphosphate)IBA 01/2013 - 06/2009
2	Small Interfering RNA (siRNA)IBA 01/2013 - 04/2007
2	Cyclin D1IBA 01/2013 - 09/2012
2	DNA (Deoxyribonucleic Acid)IBA 01/2013 - 07/2010
2	Dexamethasone (Maxidex)FDA LinkGeneric 09/2011 - 12/2009
2	Member 1 Subfamily B ATP Binding Cassette TransporterIBA 09/2011 - 09/2011
2	temsirolimus FDA Link 09/2011 - 11/2009
2	ElectrolytesIBA 09/2011 - 01/2003
2	EnzymesIBA 06/2011 - 11/2009
2	HLA Antigens (Human Leukocyte Antigens)IBA 12/2009 - 09/2003
2	Histones (Histone)IBA 03/2009 - 07/2003
2	Chlorambucil (Leukeran)FDA Link 01/2009 - 05/2006
2	Immunoglobulins (Immunoglobulin)IBA 09/2008 - 06/2005
2	Antisense OligonucleotidesIBA 06/2008 - 01/2003
2	Interleukin-2 (IL2)IBA 12/2005 - 09/2004
2	oblimersen (G3139)IBA 05/2005 - 01/2003
2	Histone Deacetylase InhibitorsIBA 02/2005 - 10/2004
2	romidepsin (FK228)FDA Link 02/2005 - 07/2003
1	venetoclaxIBA 12/2021
1	Idarubicin (4 Demethoxydaunorubicin)FDA LinkGeneric 12/2020
1	acalabrutinibIBA 12/2020
1	veliparibIBA 01/2020
1	Carboplatin (JM8)FDA LinkGeneric 01/2020
1	Hormones (Hormone)IBA 01/2020
1	ImidesIBA 01/2019
1	CreatinineIBA 01/2019
1	Vorinostat FDA Link 01/2018
1	trametinibIBA 01/2018

Therapy/Procedure

30	Therapeutics 01/2020 - 06/2003
8	Drug Therapy (Chemotherapy) 12/2020 - 01/2003
5	Renal Dialysis (Hemodialysis) 05/2015 - 11/2007
2	Aftercare (After-Treatment) 10/2015 - 01/2009
2	Drug Tapering 10/2015 - 08/2013
2	Intravenous Infusions 07/2010 - 11/2007
1	Cell Transplantation 12/2020